Why Exercise Does NOT Delay Aging?

 Why Exercise Does NOT Delay Aging?

 Science today is investigating the development of rejuvenation biotechnologies that would manage the cellular and molecular damages brought on by aging.

Compared to questionable anti-aging medications, exercise is the most sustainable way to live a healthy life and age well. Photo courtesy of Happiest Health and Anantha Subramanyam K. The quest for the elixir—or rather, elixirs—to halt or postpone aging has existed since time began. The science of aging has come a long way, down to the chromosome level. Even though rejuvenation biotechnologies are being developed to combat aging by repairing the cellular and molecular damage it causes, exercise is still your best bet for healthy aging.

Be that as it may, there is a contrast between maturing strongly and postponing maturing. With the assistance of researchers and experts from all over the world, Happiest Health dispels a few myths.

Myth 1: Physical activity delays the aging process.

According to Michael Rae, a science writer at SENS Research Foundation (Strategies for Engineered Negligible Senescence), California, USA, "Despite what is almost always said, physical activity doesn't help delay aging." Instead, despite the fact that age-related declines are the same, exercise increases physiological capacity and reserve so that when the aging process begins, you retain more functional capacity than a person your age.

An exciting analogy helps Rae, co-author of the book Ending Aging, explain this concept. Think about inflation, he says. When inflation hits, having a large savings account is a good thing because it gives you some cushion to absorb the increase in prices. In any case, the expansion in costs is happening to your buys, similarly as they are to every other person."

"In some studies, people who exercise actually see a faster rate of decline in physical performance than people who don't: Because they have a more functional reserve, they are able to maintain higher performance in the face of this faster decline.

As we get older, muscle atrophy, or the loss of muscle mass, is inevitable. Despite this, a 2008 study found that elite athletes who exercise regularly age more gracefully and have fewer health issues than those who do not.

According to Rae, exercise can therefore "increase the size and strength in surviving, functional muscle fibers" despite the fact that it "doesn't slow down the accumulation of most forms of cellular and molecular damage in the structure and unit-by-unit function of that muscle."

Myth 2: Age clocks, age calculators, and biomarkers can be used to measure age.

While wearables that track workouts and body vitals are currently popular, age calculators and clocks that measure how much exercise affects aging may be the next big thing. However, there is currently no technology that can tell you your biological age from your body's vital signs or a blood test.

Rae states, "It's not very clear we have good biomarkers of aging for individuals right now."

Lately, maturing research has collected a ton of fervor because old enough timekeepers, and explicitly epigenetic age clocks — numerically determined age assessors that are generally used to gauge the period of tissues and cells, in light old enough related compound changes in a specific region of their genomes.

According to Rae, "While a number of such clocks have been demonstrated to be fairly robust in assessing unmodified aging, it is not entirely clear yet that they accurately reflect changes in the trajectory of aging in response to interventions [such as exercise] — or that they do so uniformly."

For the same blood sample, these clocks also encounter a significant amount of technical noise (deviations). Rae claims that improved epigenetic clocks have been produced as a result of the use of computational tools, which have reduced this range of deviation to just under 1.5 years. However, the algorithm for calculating biological age will not be commercially available for some time.

Myth 3: Exercise slows down telomere attrition, thereby delaying aging.

According to Dr. Amit Sharma, leader of the ImmunoSENS group at the SENS Research Foundation, "Telomeres are little protective covers at the ends of our chromosomes," exercise slows down telomere attrition and delays aging. Telomeres shorten in length each time a cell divides as we get older, and there is no way to stop this process. Until now, no medication has been shown to repair telomeres. It is very interesting that regular exercise can slow the damage.

However, "we don't quite know how this happens yet, but it might be due to a decrease in oxidative agents in the cells that can damage the cells," although "we don't quite know how this happens." It can likewise be by further developing the capability of DNA fix chemicals", adds Dr. Sharma.

According to Rae, "Neither exercise itself nor exercise's effects on telomere attrition affect the rate of aging." Although exercise may slow the loss of telomeres,

The eventual fate of aging /maturing.

"To liberate us from maturing, we really want another foundation of biomedicines, in view of the utilization of the standards of regenerative medication to the design of the body at all levels: from organs and tissues to cells and down to the sub-atomic designs inside and encompassing them," says Rae.

"These restoration biotechnologies are treatments that straightforwardly eliminate, fix, supplant or deliver innocuous cell and atomic harm fashioned in our tissues by the natural maturing process. The progressive rise in frailty, disease, disability, and death that people now experience as they get older is caused by this damage, which gradually weakens the body's tissues over time. Functionality and youthful health and vigor can be restored by removing that damage.

Should or shouldn't you exercise?

You must, yes. Practice surely can't turn around the maturing system, yet it lessens a considerable lot of its hurtful foundational and cell impacts, as per an intricate 2015 survey.

Rae concurs. To avoid unnecessary and premature suffering from age-related disease and debility, it is very good to exercise and lead a healthy lifestyle, he says.

Conclusions

1.       Physical activity does not prevent aging. However, exercise does increase your physiological reserve, allowing you to retain more functional capacity than someone your age who experiences the same age-related decline.

2.       Although exercise cannot stop aging, it does lessen many of its systemic and cellular effects.

3.       Rejuvenation biotechnologies are treatments that directly repair, replace or remove damage to cells and molecules caused by aging.

D.G.Shastri